A New Biomaterial Derived from Small Intestine Submucosa and Developed into a Wound Matrix Device

Jump Start Wound Healing with OASIS

A New Biomaterial Derived from Small Intestine Submucosa and Developed into a Wound Matrix Device

Journal: Wounds (2002)

Authors: Marie Brown-Etris, RN, CWOCN; William D. Cutshall, MD; Michael C. Hiles, PhD3

Abstract: A biomaterial derived from porcine intestinal submucosa has been used in the development of a new biologic wound matrix. This review describes the origin of the wound matrix device, including the discovery of the biomaterial and its properties, to the development of the commercial product currently in clinical use. The composition and structure of this biomaterial are described and considered as mechanisms that contribute to its effectiveness in wound management. The wound matrix developed from this unique biomaterial was evaluated in a pilot study of human partial-thickness dermal wounds and was found to be beneficial, especially in its dehydrated form. Other applications of this biomaterial, as well as its limitations, are also discussed.

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Jump Start Wound Healing with OASIS

Journal: Wounds Supplement (2001)

Authors: Jeffrey A. Niezgoda, MD; Robert G. Frykberg, DPM; Cathy Milne, APRN, MSN; Eliot N. Mostow, MD; Marie Brown-Etris, RN; Jinsup Song, DPM, PhD

Abstract: Certainly the effective management of chronic wounds is a challenge for healthcare professionals. Issues such as confounding health problems, poor patient compliance, imbalanced nutrition, age, and lifestyle can all impact the rate and extent of wound healing. We're all aware of that puzzling phenomenon in which, even when these factors aren't at play, some wounds simply stop responding. While there's no substitute for proper wound care (assessment, debridement, etc.), we have many options beyond simple bandages and gauze to aid our management of wounds. These technologicallyadvanced options include topically applied growth factors, specially-designed hydrocolloid dressings, and bio-engineered tissues. With the introduction of Oasis Wound Dressing, Cook has expanded our options and is helping us improve treatment outcomes. Oasis is a novel, temporary wound dressing for management of partial and full-thickness skin loss injury. The product is ideal for use on pressure and chronic vascular ulcers, diabetic ulcers, second degree burns, abrasions, and autograft donor site.

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